MCL Clinical Trials
1230 trials from ClinicalTrials.gov. Recruiting trials shown first.
R-CHOP + R-HAD vs R-CHOP Followed by Maintenance Lenalidomide + Rituximab vs Rituximab for Older Patients With MCL
COMPLETEDNCT01865110·PHASE3·The Lymphoma Academic Research Organisation·623 enrolled
R-CHOPR-CHOP / R-HADRituximabLenalidomide
MORAb-004 in Treating Young Patients With Recurrent or Refractory Solid Tumors or Lymphoma
COMPLETEDNCT01748721·PHASE1·Morphotek·27 enrolled
anti-endosialin/TEM1 monoclonal antibody MORAb-004pharmacological studylaboratory biomarker analysis
Radiolabeled Monoclonal Antibody and Combination Chemotherapy Before Stem Cell Transplant in Treating Patients With High-Risk Lymphoid Malignancies
COMPLETEDNCT01921387·PHASE1 / PHASE2·Fred Hutchinson Cancer Center·20 enrolled
Autologous Hematopoietic Stem Cell TransplantationCarmustineCytarabineEtoposideLaboratory Biomarker Analysis+3 more
Pralatrexate + Romidepsin in Relapsed/Refractory Lymphoid Malignancies
COMPLETEDNCT01947140·PHASE1 / PHASE2·Jennifer Amengual·57 enrolled
PralatrexateRomidepsin
Alisertib and Romidepsin in Treating Patients With Relapsed or Refractory B-Cell or T-Cell Lymphomas
COMPLETEDNCT01897012·PHASE1·National Cancer Institute (NCI)·26 enrolled
AlisertibLaboratory Biomarker AnalysisRomidepsin
Lenalidomide With or Without Idelalisib in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma
COMPLETEDNCT01838434·PHASE1·Alliance for Clinical Trials in Oncology·106 enrolled
lenalidomideidelalisib
Entospletinib in Combination With Idelalisib in Adults With Relapsed or Refractory Hematologic Malignancies
TERMINATEDNCT01796470·PHASE2·Gilead Sciences·66 enrolled
EntospletinibIdelalisib
Vorinostat, Tacrolimus, and Methotrexate in Preventing GVHD After Stem Cell Transplant in Patients With Hematological Malignancies
COMPLETEDNCT01789255·PHASE2·National Cancer Institute (NCI)·12 enrolled
vorinostattacrolimuscyclosporinemethotrexatelaboratory biomarker analysis+1 more
Laboratory Treated T Cells in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia, Non-Hodgkin Lymphoma, or Acute Lymphoblastic Leukemia
COMPLETEDNCT01865617·PHASE1 / PHASE2·Fred Hutchinson Cancer Center·204 enrolled
Autologous Anti-CD19CAR-4-1BB-CD3zeta-EGFRt-expressing T Lymphocytes
Alisertib With and Without Rituximab in Treating Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma
TERMINATEDNCT01812005·PHASE2·Ohio State University Comprehensive Cancer Center·14 enrolled
alisertibrituximablaboratory biomarker analysis
A Study of the Bruton's Tyrosine Kinase Inhibitor Ibrutinib Given in Combination With Bendamustine and Rituximab in Patients With Newly Diagnosed Mantle Cell Lymphoma
COMPLETEDNCT01776840·PHASE3·Janssen Research & Development, LLC·523 enrolled
BendamustineRituximabIbrutinibPlacebo
Phase I/II Carfilzomib Plus Lenalidomide and Rituximab in the Treatment of Relapsed/Refractory Mantle Cell Lymphoma
TERMINATEDNCT01729104·PHASE1·M.D. Anderson Cancer Center·18 enrolled
CarfilzomibLenalidomideRituximab
Donor T Cells After Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies
COMPLETEDNCT01839916·PHASE2·University of Chicago·77 enrolled
therapeutic allogeneic lymphocyteslaboratory biomarker analysis
Treatment of Relapsed and/or Chemotherapy Refractory B-cell Malignancy by CART19
UNKNOWNNCT01864889·NA·Chinese PLA General Hospital·12 enrolled
anti-CD19-CAR vector-transduced T cells
Study of LY2835219 for Mantle Cell Lymphoma
COMPLETEDNCT01739309·PHASE2·Eli Lilly and Company·28 enrolled
Abemaciclib
Study to Evaluate Efficacy, Safety, Tolerability, and Pharmacodynamics of Entospletinib in Adults With Relapsed or Refractory Hematologic Malignancies
TERMINATEDNCT01799889·PHASE2·Gilead Sciences·326 enrolled
Entospletinib MMEntospletinib SDD
Brentuximab Vedotin + Rituximab as Frontline Therapy for Pts w/ CD30+ and/or EBV+ Lymphomas
TERMINATEDNCT01805037·PHASE1 / PHASE2·Northwestern University·20 enrolled
brentuximab vedotinrituximablaboratory biomarker analysis
Phase I Dose Escalation Study of IMMU-114 in Relapsed or Refractory NHL and CLL
TERMINATEDNCT01728207·PHASE1·Gilead Sciences·30 enrolled
IMMU-114
Study of Infusion of Blood Cells (Lymphocytes) to Stimulate the Immune System to Fight Leukemia/Lymphoma
TERMINATEDNCT01685606·PHASE2·Brown University·6 enrolled
cellular immunotherapy
Safety and Efficacy of BKM120 in Relapsed and Refractory NHL
COMPLETEDNCT01693614·PHASE2·Novartis Pharmaceuticals·72 enrolled
Buparlisib
Ipilimumab and Local Radiation for Selected Solid Tumors
TERMINATEDNCT01769222·PHASE1·Stanford University·3 enrolled
IpilimumabRadiation therapy
A Safety Study of SGN-CD19A for B-Cell Lymphoma
COMPLETEDNCT01786135·PHASE1·Seagen Inc.·64 enrolled
SGN-CD19A
Genetically Engineered Lymphocyte Therapy in Treating Patients With Lymphoma That is Resistant or Refractory to Chemotherapy
UNKNOWNNCT01735604·PHASE1 / PHASE2·Chinese PLA General Hospital·50 enrolled
anti-CD20-CAR vector-transduced autologous T cellsgenetically engineered lymphocyte therapy
Study of Ibrutinib (a Bruton's Tyrosine Kinase Inhibitor), Versus Temsirolimus in Patients With Relapsed or Refractory Mantle Cell Lymphoma Who Have Received at Least One Prior Therapy
COMPLETEDNCT01646021·PHASE3·Janssen Research & Development, LLC·280 enrolled
IbrutinibTemsirolimus
Buparlisib in Treating Patients With Relapsed or Refractory Non-Hodgkin Lymphoma
COMPLETEDNCT01719250·EARLY_PHASE1·Mayo Clinic·7 enrolled
BuparlisibLaboratory Biomarker AnalysisQuestionnaire Administration
Ublituximab in Combination With Lenalidomide in Patients With B-Cell Lymphoid Malignancies
TERMINATEDNCT01744912·PHASE1·TG Therapeutics, Inc.·10 enrolled
UblituximabLenalidomide
A Phase 1b Study Evaluating GS-9820 in Subjects With Lymphoid Malignancies
COMPLETEDNCT01705847·PHASE1·Gilead Sciences·39 enrolled
GS-9820
Vaccine Therapy in Preventing Cytomegalovirus Infection in Patients With Hematological Malignancies Undergoing Donor Stem Cell Transplant
COMPLETEDNCT01588015·PHASE1·City of Hope Medical Center·36 enrolled
tetanus-CMV fusion peptide vaccinelaboratory biomarker analysis
A Pilot Study of Oral Vorinostat Plus Oral Eltrombopag Support in Patients With Lymphoma (VEIL)
TERMINATEDNCT01500538·PHASE2·Peter MacCallum Cancer Centre, Australia·1 enrolled
Eltrombopag and Vorinostat
Donor Atorvastatin Treatment in Preventing Severe Acute GVHD After Nonmyeloablative Peripheral Blood Stem Cell Transplant in Patients With Hematological Malignancies
COMPLETEDNCT01527045·PHASE2·Fred Hutchinson Cancer Center·47 enrolled
Atorvastatin CalciumCyclosporineFludarabine PhosphateLaboratory Biomarker AnalysisMycophenolate Mofetil+3 more