MCL Clinical Trials
1230 trials from ClinicalTrials.gov. Recruiting trials shown first.
Genetically Modified Peripheral Blood Stem Cell Transplant in Treating Patients With HIV-Associated Non-Hodgkin or Hodgkin Lymphoma
WITHDRAWNNCT01769911·NA·Fred Hutchinson Cancer Center
carmustinecytarabinemelphalanetoposideO6-benzylguanine+3 more
Ibrutinib After Intensive Induction in Treating Patients With Previously Untreated Mantle Cell Lymphoma
UNKNOWNNCT02242097·PHASE2·Northwestern University·37 enrolled
ibrutiniblaboratory biomarker analysis
Acalabrutinib (ACP-196) in Combination With ACP-319, for Treatment of B-Cell Malignancies
COMPLETEDNCT02328014·PHASE1 / PHASE2·Acerta Pharma BV·40 enrolled
AcalabrutinibACP-319
CPI-613, Bendamustine Hydrochloride, and Rituximab in Treating Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma
TERMINATEDNCT02168907·PHASE1·Wake Forest University Health Sciences·1 enrolled
6,8-bis(benzylthio)octanoic acidbendamustine hydrochloriderituximablaboratory biomarker analysis
A Phase I/Ib Safety and Efficacy Study of the PI3K-delta Inhibitor TGR-1202 and Ibrutinib in Patients With CLL or MCL
COMPLETEDNCT02268851·PHASE1·Dana-Farber Cancer Institute·45 enrolled
TGR-1202Ibrutinib
Infusion of Allogeneic, 3rd Party CD19-specific T Cells
WITHDRAWNNCT02274506·PHASE1·M.D. Anderson Cancer Center
CyclophosphamideFludarabineT-Cell Infusion
Reduced Intensity Conditioning and Haploidentical Related Bone Marrow for Patients With Hematologic Diseases
TERMINATEDNCT02145039·NA·Masonic Cancer Center, University of Minnesota·2 enrolled
FludarabineCyclophosphamideTotal Body IrradiationHaploidentical stem cell transplant
Everolimus and Bendamustine Hydrochloride in Treating Patients With Relapsed or Refractory Hematologic Cancer
COMPLETEDNCT02240719·PHASE1·University of California, Davis·20 enrolled
everolimusbendamustine hydrochloride
Tissue Collection for Biomarkers Determining Resistance to Ibrutinib
UNKNOWNNCT02267590·Royal Marsden NHS Foundation Trust·120 enrolled
Phase 1 Study Evaluating ZEN003365 in Relapsed/Refractory Lymphoproliferative Malignancies or Relapsed/Refractory AML
WITHDRAWNNCT02238522·PHASE1·Zenith Epigenetics
ZEN003365
Carfilzomib Plus Belinostat in Relapsed/Refractory NHL
COMPLETEDNCT02142530·PHASE1·Massachusetts General Hospital·19 enrolled
CarfilzomibBelinostat
Ibrutinib in Treating Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma in Patients With HIV Infection
TERMINATEDNCT02109224·PHASE1·National Cancer Institute (NCI)·72 enrolled
IbrutinibLaboratory Biomarker AnalysisPharmacological Study
Safety Study of SGN-CD70A in Cancer Patients
COMPLETEDNCT02216890·PHASE1·Seagen Inc.·38 enrolled
SGN-CD70A
Study of the Bruton's Tyrosine Kinase (BTK) Inhibitor Ibrutinib in Participants With Relapsed or Refractory Mantle Cell Lymphoma
COMPLETEDNCT02169180·PHASE2·Janssen Pharmaceutical K.K.·16 enrolled
Ibrutinib
Lenalidomide and Combination Chemotherapy (DA-EPOCH-R) in Treating Patients With MYC-Associated B-Cell Lymphomas
COMPLETEDNCT02213913·PHASE1 / PHASE2·University of Chicago·55 enrolled
lenalidomideetoposideprednisonevincristine sulfatedoxorubicin hydrochloride+4 more
Study of BKM120 & Rituximab in Patients With Relapsed or Refractory Indolent B-Cell Lymphoma
COMPLETEDNCT02049541·PHASE1·Kami Maddocks, MD·18 enrolled
PI3K inhibitor BKM120rituximabPharmacodynamicsCorrelative studies
A Phase II Study of Carfilzomib in the Treatment of Relapsed/Refractory Mantle Cell Lymphoma
TERMINATEDNCT02042950·PHASE2·M.D. Anderson Cancer Center·6 enrolled
Carfilzomib
Infusion of Depleted T Cells Following Unrelated Donor Stem Cell Transplant (ICAT)
COMPLETEDNCT01827579·PHASE1 / PHASE2·University College, London·37 enrolled
CD25/71 allodepleted donor T-cells
Carfilzomib Consolidation Therapy After Autologous Stem Cell Transplantation (ASCT) for Mantle Cell Lymphoma (MCL), T-cell Lymphoma (TCL), and Diffuse Large B-Cell Lymphoma (DLBCL)
COMPLETEDNCT01926665·PHASE1·M.D. Anderson Cancer Center·2 enrolled
CarfilzomibDexamethasone
Gene Therapy for B-Cell Non-Hodgkin Lymphoma Using CD19 CAR Gene Transduced T Lymphocytes
UNKNOWNNCT02134262·PHASE1 / PHASE2·Jichi Medical University·18 enrolled
Cyclophosphamide or BendamustineDose Level -1Dose Level 1Dose Level 2Dose Level 3
ACY-1215 for Relapsed/Refractory Lymphoid Malignancies
TERMINATEDNCT02091063·PHASE1 / PHASE2·Jennifer Amengual·23 enrolled
ACY-1215
Lenalidomide Plus Rituximab Followed by Lenalidomide Versus Rituximab Maintenance for Relapsed/Refractory Follicular, Marginal Zone or Mantle Cell Lymphoma.
COMPLETEDNCT01996865·PHASE3·Celgene·503 enrolled
LenalidomideRituximab
A Phase II Study of Doxycycline in Relapsed NHL
TERMINATEDNCT02086591·PHASE2·University of Rochester·7 enrolled
Doxycycline
CART-19 Immunotherapy in Mantle Cell Lymphoma
UNKNOWNNCT02081937·PHASE1 / PHASE2·Chinese PLA General Hospital·2 enrolled
anti-CD19-CAR vector-transduced T cells
Dose Monitoring of Busulfan and Combination Chemotherapy in Hodgkin or Non-Hodgkin Lymphoma Undergoing Stem Cell Transplant
COMPLETEDNCT01959477·EARLY_PHASE1·Case Comprehensive Cancer Center·33 enrolled
busulfanetoposidecyclophosphamideperipheral blood stem cell transplantationautologous hematopoietic stem cell transplantation
Ublituximab + Ibrutinib in Select B-cell Malignancies
COMPLETEDNCT02013128·PHASE1 / PHASE2·TG Therapeutics, Inc.·66 enrolled
UblituximabIbrutinib
Single or Double Donor Umbilical Cord Blood Transplant in Treating Patients With High-Risk Hematologic Malignancies
WITHDRAWNNCT01652014·PHASE2·University of Medicine and Dentistry of New Jersey
cyclophosphamidefludarabine phosphatemycophenolate mofetilallogeneic hematopoietic stem cell transplantationumbilical cord blood transplantation+5 more
T-Regulatory Cell and CD3 Depleted Double Umbilical Cord Blood Transplantation in Hematologic Malignancies
WITHDRAWNNCT01163201·PHASE1 / PHASE2·Masonic Cancer Center, University of Minnesota
Treg cellsCD3+ Teff cellsFludarabineCyclophosphamideTotal body irradiation+1 more
DT2219ARL for Relapsed or Refractory CD19 (+), CD 22 (+) B-Lineage Leukemia Or Lymphoma
COMPLETEDNCT00889408·PHASE1·Masonic Cancer Center, University of Minnesota·25 enrolled
DT2219ARL
Romidepsin Plus Oral 5-Azacitidine in Relapsed/Refractory Lymphoid Malignancies
TERMINATEDNCT01998035·PHASE1 / PHASE2·Columbia University·58 enrolled
RomiDEPsin 10 MG/M2Oral 5-Azacitidine 100 MGRomidepsin 14 MG/M2Oral 5-Azacitidine 200 MGOral 5-Azacitidine 300 MG