MCL Clinical Trials
1230 trials from ClinicalTrials.gov. Recruiting trials shown first.
A Phase II Study of AT7519M, a CDK Inhibitor, in Patients With Relapsed Mantle Cell Lymphoma
COMPLETEDNCT01652144·PHASE2·NCIC Clinical Trials Group·12 enrolled
AT7519M
Maintenance Rituximab With mTor Inhibition After High-dose Consolidative Therapy in Lymphoma
COMPLETEDNCT01665768·PHASE2·Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins·56 enrolled
EverolimusRituximab
Belinostat and Yttrium Y 90 Ibritumomab Tiuxetan in Patients W/Relapsed Aggressive B-Cell NHL
COMPLETEDNCT01686165·PHASE2·University of Arizona·5 enrolled
belinostatrituximabyttrium Y 90 ibritumomab tiuxetan
A Study to Evaluate the Efficacy and Safety of Ibrutinib, in Patients With Mantle Cell Lymphoma Who Progress After Bortezomib Therapy
COMPLETEDNCT01599949·PHASE2·Janssen Research & Development, LLC·120 enrolled
Ibrutinib
Bendamustine/Lenalidomide/Rituximab: Combination as a Second-Line Therapy for 1st Relapsed-Refractory MCL
COMPLETEDNCT01737177·PHASE2·Fondazione Italiana Linfomi - ETS·42 enrolled
Bendamustine, Lenalidomide, Rituximab
A Study Combining Ibrutinib With Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone in Patients With CD20-Positive B-Cell Non Hodgkin Lymphoma
COMPLETEDNCT01569750·PHASE1·Janssen Research & Development, LLC·33 enrolled
Part 1, Cohort 1Part 1, Cohort 2Part 1, Cohort 3Part 2, Cohort 1Part 2, Cohort 2
Vorinostat Plus FND in Relapsed or Refractory Mantle Cell Lymphoma
TERMINATEDNCT01578343·PHASE2·Samsung Medical Center·20 enrolled
Fludarabine, Mitoxantrone, Dexamethasone, Vorinostat
Double Cord Versus Haploidentical (BMT CTN 1101)
COMPLETEDNCT01597778·PHASE3·Medical College of Wisconsin·368 enrolled
Haploidentical Bone Marrow TransplantDouble Umbilical Cord Blood Transplant
131I-rituximab for Relapsed or Refractory Follicular or Mantle Cell Lymphoma
UNKNOWNNCT01678417·PHASE2·Korea Cancer Center Hospital·29 enrolled
131I-rituximab
Mechanical Stimulation in Preventing Bone Density Loss in Patients Undergoing Donor Stem Cell Transplant
WITHDRAWNNCT01558778·NA·Roswell Park Cancer Institute
management of therapy complicationsmusculoskeletal complications management/prevention
Dasatinib for Immune Modulation After Donor Stem Cell Transplant for Hematologic Malignancies
TERMINATEDNCT01643603·PHASE1·Barbara Ann Karmanos Cancer Institute·5 enrolled
Dasatiniblaboratory biomarker analysis
Bortezomib (VELCADE), Cladribine and Rituximab (VCR) in Mantle Cell Lymphoma (PSHCI 10-011)
UNKNOWNNCT01439750·PHASE1·Milton S. Hershey Medical Center·13 enrolled
RituximabbortezomibCladribine
Lenalidomide With or Without Rituximab in Treating Patients With Progressive or Relapsed Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Prolymphocytic Leukemia, or Non-Hodgkin Lymphoma Previously Treated With Donor Stem Cell Transplant
TERMINATEDNCT01419795·PHASE2·Fred Hutchinson Cancer Center·3 enrolled
lenalidomiderituximabpharmacological studylaboratory biomarker analysis
Alisertib in Combination With Vorinostat in Treating Patients With Relapsed or Recurrent Hodgkin Lymphoma, B-Cell Non-Hodgkin Lymphoma, or Peripheral T-Cell Lymphoma
COMPLETEDNCT01567709·PHASE1·National Cancer Institute (NCI)·34 enrolled
AlisertibLaboratory Biomarker AnalysisPharmacological StudyVorinostat
Observational Study for Patients With Newly Diagnosed (MCL) Not Eligible for High-dose Therapy
COMPLETEDNCT03054883·Czech Lymphoma Study Group·73 enrolled
CD19 CAR T Cells for B Cell Malignancies After Allogeneic Transplant
COMPLETEDNCT01475058·PHASE1 / PHASE2·Fred Hutchinson Cancer Center·1 enrolled
allogeneic cytomegalovirus-specific cytotoxic T lymphocytes
Phase II Study of Age-Adjusted Rituximab, Bendamustine, Cytarabine as Induction Therapy in Older Patients With MCL
COMPLETEDNCT01662050·PHASE2·Fondazione Italiana Linfomi - ETS·57 enrolled
Rituximab, Bendamustine, Cytarabine.
Fludarabine Phosphate, Melphalan, and Low-Dose Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies
COMPLETEDNCT01529827·PHASE2·Roswell Park Cancer Institute·94 enrolled
fludarabine phosphatemelphalantotal-body irradiationtacrolimusmycophenolate mofetil+4 more
Zevalin and Velcade in Relapsed/Refractory Mantle Cell Lymphoma
TERMINATEDNCT01497275·PHASE2·Duke University·5 enrolled
Rituximab, Bortezomib,Y90 ibritumomab tiuxetan
Safety and Tolerability of HSC835 in Patients With Hematological Malignancies
COMPLETEDNCT01474681·PHASE1 / PHASE2·Novartis Pharmaceuticals·27 enrolled
HSC835
Donor Peripheral Stem Cell Transplant in Treating Patients With Hematolymphoid Malignancies
COMPLETEDNCT01523223·PHASE1·Robert Lowsky·16 enrolled
therapeutic allogeneic lymphocytes
Ofatumumab in Combination With Cyclophosphamide, Doxorubicin Hydrochloride, Vincristine Sulfate, and Dexamethasone Alternating With Ofatumumab in Combination With Cytarabine and Methotrexate in Treating Patients With Newly Diagnosed Mantle Cell Lymphoma
COMPLETEDNCT01527149·PHASE2·Roswell Park Cancer Institute·37 enrolled
Autologous Hematopoietic Stem Cell TransplantationCyclophosphamideCytarabineDexamethasoneDoxorubicin Hydrochloride+4 more
Infusion of Allogeneic CD19-Specific T Cells From Peripheral Blood
COMPLETEDNCT01497184·PHASE1·M.D. Anderson Cancer Center·95 enrolled
HSCTDLI
Study Combining SAR245409 With Rituximab or Bendamustine Plus Rituximab in Patients With Indolent Lymphoma, Mantle Cell Lymphoma and Chronic Lymphocytic Leukemia
COMPLETEDNCT01410513·PHASE1·Sanofi·37 enrolled
SAR245409
Sequential Chemo-Radioimmunotherapy Followed by Autologous Transplantation for Patients With Untreated Advanced Stage Mantle Cell Lymphoma
COMPLETEDNCT01484093·PHASE1 / PHASE2·Memorial Sloan Kettering Cancer Center·96 enrolled
R-CHOP-14R-HIDAC,followed by RIT/HDT/ASCR.
Escalating Doses of Torisel in Combination With Three Chemotherapies Regimens: R-CHOP, R-FC or R-DHA for Patients With Relapsed/Refractory Mantle Cell Lymphoma (MCL).
COMPLETEDNCT01389427·PHASE1 / PHASE2·The Lymphoma Academic Research Organisation·41 enrolled
Torisel dose 15 mg and R-CHOPTorisel dose 15 mg and R-FCTorisel dose 15 mg and R-DHATorisel dose 25 mg and R-CHOPTorisel dose 50 mg and R-CHOP+7 more
Efficacy and Safety Study of SyB L-0501 in Combination With Rituximab in Patients With Untreated, Low-grade B Cell Non-Hodgkin's Lymphoma and Mantle Cell Lymphoma
COMPLETEDNCT01718691·PHASE2·SymBio Pharmaceuticals·70 enrolled
SyB L-0501rituximab
S1106 Rituximab With Combination Chemotherapy or Bendamustine Hydrochloride Followed by Consolidation Chemotherapy and Stem Cell Transplantation in Older Patients With Previously Untreated Mantle Cell Lymphoma
COMPLETEDNCT01412879·PHASE2·SWOG Cancer Research Network·53 enrolled
rituximabbendamustine hydrochloridecyclophosphamidecytarabinedexamethasone+4 more
Bortezomib and Rituximab in Treating Patients With Mantle Cell Lymphoma Who Have Previously Undergone Stem Cell Transplantation
COMPLETEDNCT01267812·PHASE2·City of Hope Medical Center·23 enrolled
bortezomibrituximablaboratory biomarker analysisimmunohistochemistry staining methodRNA analysis+5 more
Etoposide, Filgrastim, and Plerixafor in Improving Stem Cell Mobilization in Treating Patients With Non-Hodgkin Lymphoma
TERMINATEDNCT01408043·NA·Case Comprehensive Cancer Center·25 enrolled
plerixaforfilgrastimetoposideleukapheresis