MCL Clinical Trials
1230 trials from ClinicalTrials.gov. Recruiting trials shown first.
TLR9 Agonist SD-101, Ibrutinib, and Radiation Therapy in Treating Patients With Relapsed or Refractory Grade 1-3A Follicular Lymphoma
COMPLETEDNCT02927964·PHASE1 / PHASE2·Robert Lowsky·21 enrolled
IbrutinibRadiation TherapyTLR9 Agonist SD-101
Efficacy and Safety of Ibrutinib in Patients With CLL and Other Indolent B-cell Lymphomas Who Are Chronic Hepatitis B Virus Carriers or Occult Hepatitis B Virus Carriers
UNKNOWNNCT02991638·PHASE3·The University of Hong Kong·62 enrolled
Ibrutinib
Ibrutinib in Treating Patients With Refractory or Relapsed Lymphoma After Donor Stem Cell Transplant
COMPLETEDNCT02869633·PHASE2·Vanderbilt-Ingram Cancer Center·23 enrolled
IbrutinibLaboratory Biomarker Analysis
A Study in Advanced Cancers Using Ramucirumab (LY3009806) and Other Targeted Agents
COMPLETEDNCT02745769·PHASE1·Eli Lilly and Company·23 enrolled
RamucirumabMerestinibAbemaciclib
Trial of Bortezomib, Cytarabine, and Dexamethasone in Mantle Cell Lymphoma
COMPLETEDNCT02840539·PHASE2·Seoul National University Hospital·19 enrolled
Bortezomib, Cytarabine, Dexamethasone, Pegteograstim
A Study of ME-401 in Subjects With CLL/SLL, FL, and B-cell Non Hodgkin's Lymphoma
TERMINATEDNCT02914938·PHASE1·MEI Pharma, Inc.·97 enrolled
ME-401RituximabZanubrutinib
Study to Evaluate Safety and Tolerability of XmAb13676 (Plamotamab) in Patients With CD20-expressing Hematologic Malignancies
COMPLETEDNCT02924402·PHASE1·Xencor, Inc.·154 enrolled
XmAb13676
CAR-T Cell Immunotherapy in CD19 Positive Relapsed or Refractory Leukemia and Lymphoma
UNKNOWNNCT02819583·PHASE1 / PHASE2·PersonGen BioTherapeutics (Suzhou) Co., Ltd.·10 enrolled
PCAR-019 (anti-CD19 CAR-T cells)
Rituximab, Romidepsin, and Lenalidomide in Treating Patients With Recurrent or Refractory B-cell Non-Hodgkin Lymphoma
WITHDRAWNNCT02281279·PHASE1 / PHASE2·Mayo Clinic
rituximablenalidomideromidepsinlaboratory biomarker analysis
Tacrolimus, Bortezomib, & Thymoglobulin in Preventing Low Toxicity GVHD in Donor Blood Stem Cell Transplant Patients
TERMINATEDNCT02877082·PHASE2·Emory University·5 enrolled
ThymoglobulinBortezomibTacrolimus
PCAR-119 Bridge Immunotherapy Prior to Stem Cell Transplant in Treating Patients With CD19 Positive Leukemia and Lymphoma
UNKNOWNNCT02892695·PHASE1 / PHASE2·PersonGen BioTherapeutics (Suzhou) Co., Ltd.·10 enrolled
anti-CD19 CAR-NK cells
Phase I/II, FIH, Dose Escalation Trial of TL-895 and Expansion of TL-895 Monotherapy and Combination Therapy With Navtemadlin in Tx-Naïve and R/R CLL/SLL Subjects
UNKNOWNNCT02825836·PHASE1 / PHASE2·Telios Pharma, Inc.·130 enrolled
TL-895Navtemadlin
Study of the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of Duvortuxizumab (JNJ-64052781) Plus Ibrutinib in Lymphoma
WITHDRAWNNCT02743546·PHASE1·Janssen Research & Development, LLC
DuvortuxizumabIbrutinib
Obinutuzumab in Combination With Ibrutinib in Treating Patients With Relapsed Mantle Cell Lymphoma
COMPLETEDNCT02736617·PHASE2·OHSU Knight Cancer Institute·10 enrolled
IbrutinibObinutuzumab
Study Evaluating the Efficacy and Safety of PCAR-019 in CD19 Positive Relapsed or Refractory Leukemia and Lymphoma
UNKNOWNNCT02851589·PHASE1 / PHASE2·PersonGen BioTherapeutics (Suzhou) Co., Ltd.·10 enrolled
PCAR-019 (anti-CD19 CAR-T cells)
Treg Cells for AGVHD in Non-myeloablative UCB Transplant
WITHDRAWNNCT02118311·PHASE2·Masonic Cancer Center, University of Minnesota
T Regulatory cellsFludarabineCyclophosphamideTotal Body Irradiation
Study to Assess the Efficacy and Safety of Ublituximab + Umbralisib With or Without Bendamustine and Umbralisib Alone in Patients With Previously Treated Non-Hodgkins Lymphoma
TERMINATEDNCT02793583·PHASE2 / PHASE3·TG Therapeutics, Inc.·710 enrolled
UblituximabUmbralisibBendamustine
A Study to Determine Dose, Safety, and Efficacy of Durvalumab as Monotherapy and in Combination Therapy in Subjects With Lymphoma or Chronic Lymphocytic Leukemia
COMPLETEDNCT02733042·PHASE1 / PHASE2·Celgene·106 enrolled
DurvalumabLenalidomideRituximabIbrutinibBendamustine
A Study of Ibrutinib in the Treatment of Chronic Lymphocytic Leukemia and Mantle-cell Lymphoma in Routine Clinical Practice
COMPLETEDNCT03425591·Janssen-Cilag Ltd.·508 enrolled
Ibrutinib
A Clinical Trial of Buparlisib and Ibrutinib in Lymphoma
COMPLETEDNCT02756247·PHASE1·Memorial Sloan Kettering Cancer Center·37 enrolled
BuparlisibIbrutinib
A Study of Acalabrutinib in Combination With Rituximab Versus Ibrutinib Versus Acalabrutinib in Subjects With Relapsed or Refractory Mantle Cell Lymphoma
WITHDRAWNNCT02735876·PHASE3·Acerta Pharma BV
acalabrutinibibrutinibrituximab
Bendamustine and Rituximab Alternating With Cytarabine and Rituximab for Untreated Mantle Cell Lymphoma
COMPLETEDNCT02728531·PHASE1·Washington University School of Medicine·18 enrolled
BendamustineRituximabCytarabinePegfilgrastimLeukapheresis+2 more
Phase 2 Study of AT13387 (Onalespib) in ALK+ ALCL, MCL, and BCL-6+ DLBCL
TERMINATEDNCT02572453·PHASE2·National Cancer Institute (NCI)·25 enrolled
Onalespib
Genetically Modified T-Cell Therapy in Treating Patients With Advanced ROR1+ Malignancies
TERMINATEDNCT02706392·PHASE1·Fred Hutchinson Cancer Center·21 enrolled
Laboratory Biomarker AnalysisROR1 CAR-specific Autologous T-Lymphocytes
Ixazomib & Rituximab After Stem Cell Transplant in Treating Patients With Mantle Cell Lymphoma in Remission
UNKNOWNNCT02632396·PHASE1 / PHASE2·Emory University·12 enrolled
IxazomibRituximab
Anti-CD22 CAR-T Therapy for CD19-refractory or Resistant Lymphoma Patients
UNKNOWNNCT02721407·PHASE1·Xinqiao Hospital of Chongqing·20 enrolled
Retroviral vector-transduced autologous T cells to express CD22-specific CARs
Study of ADCT-402 in Patients With Relapsed or Refractory B-cell Lineage Non Hodgkin Lymphoma (B-NHL)
COMPLETEDNCT02669017·PHASE1·ADC Therapeutics S.A.·183 enrolled
ADCT-402
Phase I Dose Escalation Study for VIP152 in Patients With Advanced Cancer
COMPLETEDNCT02635672·PHASE1·Vincerx Pharma, Inc.·110 enrolled
VIP152 (BAY 1251152)VIP152 (BAY 1251152) 30 mgKeytrudaVIP152 (BAY 1251152) 15 mg
Competitive Transfer of αCD19-TCRz-CD28 and αCD19-TCRz-CD137 CAR-T Cells for B-cell Leukemia/Lymphoma
UNKNOWNNCT02685670·PHASE1 / PHASE2·The Second Affiliated Hospital of Henan University of Traditional Chinese Medicine·20 enrolled
anti-CD19 CAR-TFludarabineCyclophosphamide
Salvia Hispanica Seed in Reducing Risk of Disease Recurrence in Patients With Non-Hodgkin Lymphoma
COMPLETEDNCT02652715·NA·Mayo Clinic·29 enrolled
Laboratory Biomarker AnalysisQuality-of-Life AssessmentQuestionnaire AdministrationSalvia hispanica Seed