MCL Clinical Trials
1230 trials from ClinicalTrials.gov. Recruiting trials shown first.
Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of AMG 562 in Subjects With r/r Diffuse Large B-cell Lymphoma, Mantle Cell Lymphoma, or Follicular Lymphoma
TERMINATEDNCT03571828·PHASE1·Amgen·10 enrolled
AMG 562
Study of TRPH-222 in Patients With Relapsed and/or Refractory B-Cell Lymphoma
COMPLETEDNCT03682796·PHASE1·Triphase Research and Development III Corp.·32 enrolled
TRPH-222
A Pilot Investigator-Initiated Study of Ribavirin in Indolent Follicular Lymphoma and Mantle Cell Lymphoma
TERMINATEDNCT03585725·EARLY_PHASE1·Weill Medical College of Cornell University·3 enrolled
Ribavirin
Clinical Follow-up Study of CD19 CAR-T Expressing IL7 and CCL19 for Relapsed or Refractory B Cell Lymphoma
COMPLETEDNCT04833504·Second Affiliated Hospital, School of Medicine, Zhejiang University·39 enrolled
CD19 CAR-T Expressing IL7 and CCL19
Lenalidomide Observational Study in Patients With Mantle Lymphoma in Relapse/Refraction. Spanish Programme RRMCL Results.
UNKNOWNNCT04109872·Fundación Pública Andaluza para la gestión de la Investigación en Sevilla·25 enrolled
Lenalidomide
Rituximab, Bendamustine and Cytarabine Followed by Venetoclax in High Risk Elderly Patients With MCL
COMPLETEDNCT03567876·PHASE2·Fondazione Italiana Linfomi - ETS·141 enrolled
Venetoclax
A Study of Ixazomib and Ibrutinib in Relapsed/Refractory Mantle Cell Lymphoma
COMPLETEDNCT03323151·PHASE1 / PHASE2·PrECOG, LLC.·43 enrolled
IxazomibIxazomibIbrutinibIbrutinib
A Study of INCB050465 in Japanese Subjects With Previously Treated B-Cell Lymphoma (CITADEL-111)
COMPLETEDNCT03314922·PHASE1·Incyte Corporation·17 enrolled
Parsaclisib
Idelalisib Post Allogeneic Hematopoietic Stem Cell Transplant (HSCT) in B Cell Derived Malignancies
TERMINATEDNCT03151057·PHASE1·Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins·16 enrolled
Idelalisib 100 MGPlacebo Oral Tablet
INCB050465 in Combination With Rituximab, Bendamustine and Rituximab, or Ibrutinib in Participants With Previously Treated B-Cell Lymphoma (CITADEL-112)
COMPLETEDNCT03424122·PHASE1·Incyte Corporation·50 enrolled
ParsaclisibRituximabBendamustineIbrutinib
Venetoclax, Lenalidomide and Rituximab in Patients With Relapsed/Refractory Mantle Cell Lymphoma
UNKNOWNNCT03505944·PHASE1 / PHASE2·Nordic Lymphoma Group·59 enrolled
Venetoclax
Open-Label, Multi-Center, Two-Part, Ph1 Study to Characterize the PKs of an Intravenous Micro-Dose of [14C]-Tazemetostat (EPZ 6438) and the ADME of an Oral [14C]-Labeled Dose of Tazemetostat in Subjects With B-Cell Lymphomas or Adv Solid Tumors
COMPLETEDNCT03010982·PHASE1·Epizyme, Inc.·3 enrolled
Tazemetostat and [14C] Tazemetostat
A Study of Voruciclib Alone or in Combination With Venetoclax in Subjects With B-Cell Malignancies or AML
TERMINATEDNCT03547115·PHASE1·MEI Pharma, Inc.·84 enrolled
voruciclib monotherapyvoruciclib and venetoclax
Efficacy and Safety of Obinutuzumab Preemptive Treatment at the Time of the Molecular Relapse
TERMINATEDNCT03229382·PHASE2·Polish Lymphoma Research Group·1 enrolled
Obinutuzumab
Clinical Outcomes of Chronic Lymphocytic Leukemia (CCL) and Mantle Cell Lymphoma (MCL) Participants Treated With Ibrutinib: A Medical Chart Review From India
COMPLETEDNCT03476655·Johnson & Johnson Private Limited·40 enrolled
Ibrutinib
TLR9 Agonist SD-101, Anti-OX40 Antibody BMS 986178, and Radiation Therapy in Treating Patients With Low-Grade B-Cell Non-Hodgkin Lymphomas
COMPLETEDNCT03410901·PHASE1·Ronald Levy·14 enrolled
Anti-OX40 Antibody BMS 986178Laboratory Biomarker AnalysisRadiation TherapyTLR9 Agonist SD-101
Avelumab, Utomilumab, Rituximab, Ibrutinib, and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma or Mantle Cell Lymphoma
COMPLETEDNCT03440567·PHASE1·City of Hope Medical Center·16 enrolled
Autologous Hematopoietic Stem Cell TransplantationAvelumabCarboplatinEtoposide PhosphateIbrutinib+4 more
A Study to Evaluate ICP-022 in Patients With R/R Mantle Cell Lymphoma (MCL)
UNKNOWNNCT03494179·PHASE1 / PHASE2·Beijing InnoCare Pharma Tech Co., Ltd.·120 enrolled
ICP-022
GRAVITAS-119: Itacitinib in Combination With Calcineurin Inhibitor-Based Interventions for the Prophylaxis of Graft-Versus Host Disease
TERMINATEDNCT03320642·PHASE1·Incyte Corporation·84 enrolled
ItacitinibCalcineurin inhibitor
Study of STRO-001, an Anti-CD74 Antibody Drug Conjugate, in Patients With Advanced B-Cell Malignancies
COMPLETEDNCT03424603·PHASE1·Sutro Biopharma, Inc.·70 enrolled
STRO-001
Long-term Follow-up Study for Patients Previously Treated With a Juno CAR T-Cell Product
TERMINATEDNCT03436771·Juno Therapeutics, a Subsidiary of Celgene·4 enrolled
JCAR017JCARH125
Efficacy and Safety of Chi-BEAC Combining With Auto-HSCT to Treat Aggressive Lymphoma Subjects
UNKNOWNNCT03629873·PHASE2·The First Affiliated Hospital with Nanjing Medical University·69 enrolled
Chidamide
The Clinical Application of Chimeric Antigen Receptor T Cells in the Treatment of CD19 Positive Recurrent Refractory B Cell-derived Hematological Malignancies
UNKNOWNNCT04184414·EARLY_PHASE1·PersonGen BioTherapeutics (Suzhou) Co., Ltd.·10 enrolled
CD19-CART
A Study of Cirmtuzumab and Ibrutinib in Patients With B-Cell Lymphoid Malignancies
COMPLETEDNCT03088878·PHASE1 / PHASE2·Oncternal Therapeutics, Inc·95 enrolled
Cirmtuzumab (2-16 kg/mg) plus IbrutinibCirmtuzumab (300mg) plus IbrutinibCirmtuzumab (600 mg) plus ibrutinibCirmtuzumab (RDR) plus ibrutinibCirmtuzumab plus ibrutinib+1 more
Dosimetry Study of Betalutin for Treatment of Relapsed Non-Hodgkin Lymphoma (LYMRIT-37-02)
WITHDRAWNNCT02657447·PHASE1·Nordic Nanovector
Betalutin with lilotomab dose 1Betalutin with lilotomab dose 2
A Study of CDX-1140 (CD40) as Monotherapy or in Combination in Patients With Advanced Malignancies
COMPLETEDNCT03329950·PHASE1·Celldex Therapeutics·132 enrolled
CDX-1140CDX-301pembrolizumabChemotherapy
A Study of INCB050465 in Relapsed or Refractory Mantle Cell Lymphoma Previously Treated With or Without a Bruton's Tyrosine Kinase (BTK) Inhibitor
COMPLETEDNCT03235544·PHASE2·Incyte Corporation·162 enrolled
Parsaclisib
Ph I Trial of NAM NK Cells and IL-2 for Adult Pts With MM and NHL
COMPLETEDNCT03019666·PHASE1·Masonic Cancer Center, University of Minnesota·39 enrolled
Nicotinamide Expanded Haploidentical or Mismatched Related Donor Natural Killer Cells
Umbilical Cord Blood NK Cells, Rituximab, High-Dose Chemotherapy, and Stem Cell Transplant in Treating Patients With Recurrent or Refractory B-Cell Non-Hodgkin's Lymphoma
COMPLETEDNCT03019640·PHASE2·M.D. Anderson Cancer Center·22 enrolled
Autologous Hematopoietic Stem Cell TransplantationCarmustineCord Blood-derived Expanded Allogeneic Natural Killer CellsCytarabineEtoposide+4 more
Bendamustine + Obinutuzumab Induction With Obinutuzumab Maintenance in Untreated Mantle Cell Lymphoma
TERMINATEDNCT03311126·PHASE2·University of Wisconsin, Madison·21 enrolled
BendamustineObinutuzumab