MCL Clinical Trials
1230 trials from ClinicalTrials.gov. Recruiting trials shown first.
Immune Responses to COVID-19 Vaccination in Lymphoma Patients
COMPLETEDNCT04858568·University Hospital Southampton NHS Foundation Trust·592 enrolled
A Phase 1 Study of ADI-001 in B Cell Malignancies
TERMINATEDNCT04735471·PHASE1·Adicet Therapeutics·34 enrolled
ADI-001FludarabineCyclophosphamide
Interrogating Biological Signaling Pathway Dysregulations and In Vitro Screening With Personalized Therapies in Relapsed or Refractory Mantle Cell Lymphoma, MCL MATCH Trial
COMPLETEDNCT04872413·NA·M.D. Anderson Cancer Center·1 enrolled
Biospecimen CollectionFollow-Up
APR-246 in Combination With Acalabrutinib or Venetoclax Based Therapy in Subjects With R/R Non Hodgkin Lymphomas (NHL)
TERMINATEDNCT04419389·PHASE1 / PHASE2·Aprea Therapeutics·1 enrolled
APR-246 (eprenetapopt) + Acalabrutinib in CLLAPR-246 (eprenetapopt) 4.5 g/d + Venetoclax + Rituximab in CLLAPR-246 (eprenetapopt) 4.5 g/d + (Acalabrutinib, OR, (Venetoclax +Rituximab)), in CLL and/or MCL and/or RTAPR-246 (eprenetapopt) 4.5 g/d + Venetoclax + Rituximab in RT
RPM CD19-mbIL15-CAR-T Cells in Patient With Advanced Lymphoid Malignancies
TERMINATEDNCT04844086·PHASE1·Eden BioCell Ltd.·2 enrolled
RPM CD19-mbIL15-CAR-T cells
Study of Zanubrutinib, Rituximab and Combination Chemotherapy in Newly-diagnosed Aggressive B-cell Non-Hodgkin Lymphoma
UNKNOWNNCT05164770·PHASE3·Shandong Provincial Hospital·160 enrolled
Zanubrutinib+R-CHOP; Zanubrutinib+R-DA-EPOCH; Zanubrutinib+R-HD MTXR-CHOP; R-DA-EPOCH; R-HD MTX
Safety and Efficacy of CT125A Cells for Treatment of Relapsed/Refractory CD5+ Hematopoietic Malignancies
UNKNOWNNCT04767308·EARLY_PHASE1·Huazhong University of Science and Technology·18 enrolled
CT125A cellsCyclophosphamide, fludarabine
Effects of Prebiotics on Gut Microbiome in Patients Undergoing HSCT
COMPLETEDNCT04629430·NA·University of Virginia·40 enrolled
Pre-biotic foods/drinks
Zanubrutinib-based Induction and Maintenance Therapy in Young and Fit Patients With Untreated Mantle Cell Lymphoma
UNKNOWNNCT04736914·PHASE2·Sun Yat-sen University·47 enrolled
R-CHOP/R-DHAOx; Zanubrutib(induction); ASCT conditioning ; Zanubrutinib(Maintenance)
Long-term Follow-up Study for Patients Treated With CLBR001 CAR-T
COMPLETEDNCT04488354·PHASE1·Calibr, a division of Scripps Research·16 enrolled
CLBR001 and SWI019
Ibrutinib Combined With Bendamustine and Rituximab in Newly Diagnosed Mantle Cell Lymphoma Patients Who Aged > 65 Years
UNKNOWNNCT05406154·Peking University Third Hospital·60 enrolled
Ibrutinib Combined With R-CHOP/R-DHAP in Newly Diagnosed Mantle Cell Lymphoma Patients Who Aged ≤65 Years
UNKNOWNNCT05429918·Peking University Third Hospital·60 enrolled
Study of LUCAR-20S in Patients With R/R NHL
TERMINATEDNCT04176913·PHASE1·The First Affiliated Hospital with Nanjing Medical University·7 enrolled
LUCAR-20S CAR-T cells
Ibrutinib for the Treatment of Patients With B-Cell Malignancies Who Are Infected With Coronavirus Disease 2019 (COVID-19)
WITHDRAWNNCT04665115·PHASE2·Academic and Community Cancer Research United
IbrutinibQuality-of-Life Assessment
The Role of 18F-FDG-PET for Staging and Prognostication
COMPLETEDNCT04600804·Fondazione Italiana Linfomi - ETS·200 enrolled
Irradiated Donor Cells Following Stem Cell Transplant in Controlling Cancer in Patients With Hematologic Malignancies
TERMINATEDNCT03272633·EARLY_PHASE1·Rutgers, The State University of New Jersey·2 enrolled
Allogeneic Hematopoietic Stem Cell TransplantationIrradiated Allogeneic Cells
CC-486, Lenalidomide, and Obinutuzumab for the Treatment of Recurrent or Refractory CD20 Positive B-cell Lymphoma
COMPLETEDNCT04578600·PHASE1·Joseph Tuscano·8 enrolled
LenalidomideObinutuzumabOral Azacitidine
A Study in Healthy Subjects to Assess Bioavailability (Proportion of a Drug Which Enters the Circulation to Have an Active Effect) of Acalabrutinib Tablet and Protonpump Inhibitor Effect (Members of a Class of Medications That Inhibits in Gastric Acid Production) for Rabeprazole
COMPLETEDNCT04564040·PHASE1·AstraZeneca·20 enrolled
Acalabrutinib Treatment AAcalabrutinib Treatment BAcalabrutinib Treatment CAcalabrutinib Treatment D
Study to Assess Effect of Oral Venetoclax Tablet in Combination With Oral Ibrutinib Capsule on Best Overall Response of Complete Response in Adult Japanese Participants With Relapsed/Refractory Mantle Cell Lymphoma
COMPLETEDNCT04477486·PHASE2·AbbVie·13 enrolled
IbrutinibVenetoclax
CLBR001 and SWI019 in Patients With Relapsed / Refractory B-cell Malignancies
COMPLETEDNCT04450069·PHASE1·Calibr, a division of Scripps Research·18 enrolled
CLBR001 and SWI019
Treatment With Acalabrutinib Post Blood or Marrow Transplantation in Subjects With Mantle Cell Lymphoma
COMPLETEDNCT04402138·PHASE2·SCRI Development Innovations, LLC·15 enrolled
Acalabrutinib
Zanubrutinib-rituximab(ZR) in Patients With Newly Diagnosed Untreated Mantle Cell Lymphoma
UNKNOWNNCT05504603·PHASE2·The First Affiliated Hospital of Soochow University·20 enrolled
zanubrutinib and rituximabzanubrutinib and rituximabBEAM pretreatmentzanubrutinib maintenance
A Study of TQ-B3525 Tablet in the Treatment of Relapsed / Refractory Mantle Cell Lymphoma (MCL)
UNKNOWNNCT04398953·PHASE2·Chia Tai Tianqing Pharmaceutical Group Co., Ltd.·102 enrolled
TQ-B3525
Bortezomib in Combination With Ibrutinib in Ibrutinib Relapsed Mantle Cell Lymphoma
WITHDRAWNNCT03617484·PHASE2·University of Michigan Rogel Cancer Center
BortezomibIbrutinib
CD19-Specific T Cells Post AlloSCT
TERMINATEDNCT03579888·PHASE1·M.D. Anderson Cancer Center·4 enrolled
Autologous CD19-CD8-CD28-CD3zeta-CAR-mbIL15-HER1t T CellsCyclophosphamideFludarabine
A Phase Ib Study of YY-20394 in Participants With B-cell Hematologic Malignancies
COMPLETEDNCT04279405·PHASE1·Shanghai YingLi Pharmaceutical Co. Ltd.·43 enrolled
YY-20394
Atrial Fibrillation in Patients Receiving Ibrutinib
UNKNOWNNCT04407845·European Georges Pompidou Hospital·60 enrolled
Study of BGB-10188 as Monotherapy, and in Combination With Zanubrutinib, and Tislelizumab
COMPLETEDNCT04282018·PHASE1 / PHASE2·BeiGene·97 enrolled
BGB-10188ZanubrutinibTislelizumab
TC-110 T Cells in Adults With Relapsed or Refractory Non-Hodgkin Lymphoma or Acute Lymphoblastic Leukemia
COMPLETEDNCT04323657·PHASE1 / PHASE2·TCR2 Therapeutics·6 enrolled
TC-110 T CellsFludarabineCyclophosphamide
First-in-Human (FIH) Trial of GEN3009 in Subjects With Relapsed or Refractory B-Cell Non-Hodgkin Lymphomas
TERMINATEDNCT04358458·PHASE1 / PHASE2·Genmab·46 enrolled
GEN3009Epcoritamab