t(11;14)

MCL Clinical Trials

1230 trials from ClinicalTrials.gov. Recruiting trials shown first.

Immune Responses to COVID-19 Vaccination in Lymphoma Patients
COMPLETED
NCT04858568·University Hospital Southampton NHS Foundation Trust·592 enrolled
A Phase 1 Study of ADI-001 in B Cell Malignancies
TERMINATED
NCT04735471·PHASE1·Adicet Therapeutics·34 enrolled
ADI-001FludarabineCyclophosphamide
Interrogating Biological Signaling Pathway Dysregulations and In Vitro Screening With Personalized Therapies in Relapsed or Refractory Mantle Cell Lymphoma, MCL MATCH Trial
COMPLETED
NCT04872413·NA·M.D. Anderson Cancer Center·1 enrolled
Biospecimen CollectionFollow-Up
APR-246 in Combination With Acalabrutinib or Venetoclax Based Therapy in Subjects With R/R Non Hodgkin Lymphomas (NHL)
TERMINATED
NCT04419389·PHASE1 / PHASE2·Aprea Therapeutics·1 enrolled
APR-246 (eprenetapopt) + Acalabrutinib in CLLAPR-246 (eprenetapopt) 4.5 g/d + Venetoclax + Rituximab in CLLAPR-246 (eprenetapopt) 4.5 g/d + (Acalabrutinib, OR, (Venetoclax +Rituximab)), in CLL and/or MCL and/or RTAPR-246 (eprenetapopt) 4.5 g/d + Venetoclax + Rituximab in RT
RPM CD19-mbIL15-CAR-T Cells in Patient With Advanced Lymphoid Malignancies
TERMINATED
NCT04844086·PHASE1·Eden BioCell Ltd.·2 enrolled
RPM CD19-mbIL15-CAR-T cells
Study of Zanubrutinib, Rituximab and Combination Chemotherapy in Newly-diagnosed Aggressive B-cell Non-Hodgkin Lymphoma
UNKNOWN
NCT05164770·PHASE3·Shandong Provincial Hospital·160 enrolled
Zanubrutinib+R-CHOP; Zanubrutinib+R-DA-EPOCH; Zanubrutinib+R-HD MTXR-CHOP; R-DA-EPOCH; R-HD MTX
Safety and Efficacy of CT125A Cells for Treatment of Relapsed/Refractory CD5+ Hematopoietic Malignancies
UNKNOWN
NCT04767308·EARLY_PHASE1·Huazhong University of Science and Technology·18 enrolled
CT125A cellsCyclophosphamide, fludarabine
Effects of Prebiotics on Gut Microbiome in Patients Undergoing HSCT
COMPLETED
NCT04629430·NA·University of Virginia·40 enrolled
Pre-biotic foods/drinks
Zanubrutinib-based Induction and Maintenance Therapy in Young and Fit Patients With Untreated Mantle Cell Lymphoma
UNKNOWN
NCT04736914·PHASE2·Sun Yat-sen University·47 enrolled
R-CHOP/R-DHAOx; Zanubrutib(induction); ASCT conditioning ; Zanubrutinib(Maintenance)
Long-term Follow-up Study for Patients Treated With CLBR001 CAR-T
COMPLETED
NCT04488354·PHASE1·Calibr, a division of Scripps Research·16 enrolled
CLBR001 and SWI019
Ibrutinib Combined With Bendamustine and Rituximab in Newly Diagnosed Mantle Cell Lymphoma Patients Who Aged > 65 Years
UNKNOWN
NCT05406154·Peking University Third Hospital·60 enrolled
Ibrutinib Combined With R-CHOP/R-DHAP in Newly Diagnosed Mantle Cell Lymphoma Patients Who Aged ≤65 Years
UNKNOWN
NCT05429918·Peking University Third Hospital·60 enrolled
Study of LUCAR-20S in Patients With R/R NHL
TERMINATED
NCT04176913·PHASE1·The First Affiliated Hospital with Nanjing Medical University·7 enrolled
LUCAR-20S CAR-T cells
Ibrutinib for the Treatment of Patients With B-Cell Malignancies Who Are Infected With Coronavirus Disease 2019 (COVID-19)
WITHDRAWN
NCT04665115·PHASE2·Academic and Community Cancer Research United
IbrutinibQuality-of-Life Assessment
The Role of 18F-FDG-PET for Staging and Prognostication
COMPLETED
NCT04600804·Fondazione Italiana Linfomi - ETS·200 enrolled
Irradiated Donor Cells Following Stem Cell Transplant in Controlling Cancer in Patients With Hematologic Malignancies
TERMINATED
NCT03272633·EARLY_PHASE1·Rutgers, The State University of New Jersey·2 enrolled
Allogeneic Hematopoietic Stem Cell TransplantationIrradiated Allogeneic Cells
CC-486, Lenalidomide, and Obinutuzumab for the Treatment of Recurrent or Refractory CD20 Positive B-cell Lymphoma
COMPLETED
NCT04578600·PHASE1·Joseph Tuscano·8 enrolled
LenalidomideObinutuzumabOral Azacitidine
A Study in Healthy Subjects to Assess Bioavailability (Proportion of a Drug Which Enters the Circulation to Have an Active Effect) of Acalabrutinib Tablet and Protonpump Inhibitor Effect (Members of a Class of Medications That Inhibits in Gastric Acid Production) for Rabeprazole
COMPLETED
NCT04564040·PHASE1·AstraZeneca·20 enrolled
Acalabrutinib Treatment AAcalabrutinib Treatment BAcalabrutinib Treatment CAcalabrutinib Treatment D
Study to Assess Effect of Oral Venetoclax Tablet in Combination With Oral Ibrutinib Capsule on Best Overall Response of Complete Response in Adult Japanese Participants With Relapsed/Refractory Mantle Cell Lymphoma
COMPLETED
NCT04477486·PHASE2·AbbVie·13 enrolled
IbrutinibVenetoclax
CLBR001 and SWI019 in Patients With Relapsed / Refractory B-cell Malignancies
COMPLETED
NCT04450069·PHASE1·Calibr, a division of Scripps Research·18 enrolled
CLBR001 and SWI019
Treatment With Acalabrutinib Post Blood or Marrow Transplantation in Subjects With Mantle Cell Lymphoma
COMPLETED
NCT04402138·PHASE2·SCRI Development Innovations, LLC·15 enrolled
Acalabrutinib
Zanubrutinib-rituximab(ZR) in Patients With Newly Diagnosed Untreated Mantle Cell Lymphoma
UNKNOWN
NCT05504603·PHASE2·The First Affiliated Hospital of Soochow University·20 enrolled
zanubrutinib and rituximabzanubrutinib and rituximabBEAM pretreatmentzanubrutinib maintenance
A Study of TQ-B3525 Tablet in the Treatment of Relapsed / Refractory Mantle Cell Lymphoma (MCL)
UNKNOWN
NCT04398953·PHASE2·Chia Tai Tianqing Pharmaceutical Group Co., Ltd.·102 enrolled
TQ-B3525
Bortezomib in Combination With Ibrutinib in Ibrutinib Relapsed Mantle Cell Lymphoma
WITHDRAWN
NCT03617484·PHASE2·University of Michigan Rogel Cancer Center
BortezomibIbrutinib
CD19-Specific T Cells Post AlloSCT
TERMINATED
NCT03579888·PHASE1·M.D. Anderson Cancer Center·4 enrolled
Autologous CD19-CD8-CD28-CD3zeta-CAR-mbIL15-HER1t T CellsCyclophosphamideFludarabine
A Phase Ib Study of YY-20394 in Participants With B-cell Hematologic Malignancies
COMPLETED
NCT04279405·PHASE1·Shanghai YingLi Pharmaceutical Co. Ltd.·43 enrolled
YY-20394
Atrial Fibrillation in Patients Receiving Ibrutinib
UNKNOWN
NCT04407845·European Georges Pompidou Hospital·60 enrolled
Study of BGB-10188 as Monotherapy, and in Combination With Zanubrutinib, and Tislelizumab
COMPLETED
NCT04282018·PHASE1 / PHASE2·BeiGene·97 enrolled
BGB-10188ZanubrutinibTislelizumab
TC-110 T Cells in Adults With Relapsed or Refractory Non-Hodgkin Lymphoma or Acute Lymphoblastic Leukemia
COMPLETED
NCT04323657·PHASE1 / PHASE2·TCR2 Therapeutics·6 enrolled
TC-110 T CellsFludarabineCyclophosphamide
First-in-Human (FIH) Trial of GEN3009 in Subjects With Relapsed or Refractory B-Cell Non-Hodgkin Lymphomas
TERMINATED
NCT04358458·PHASE1 / PHASE2·Genmab·46 enrolled
GEN3009Epcoritamab