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Preetesh Jain

Assistant Professor, Department of Lymphoma and Myeloma

MD Anderson Cancer Center · Houston, United States

About

Rising MCL expert at MD Anderson focused on novel combinations and outcomes in high-risk MCL, particularly TP53-mutated disease. Published extensively on BTK inhibitor resistance and bispecific antibodies.

Specialties
BTK inhibitorsBispecificsRelapsed/refractory MCLTP53-mutated MCL
Key Trials
BOVenPirtobrutinib studies
Publications (22)

Correction: Exploiting PRMT5 as a target for combination therapy in mantle cell lymphoma characterized by frequent ATM and TP53 mutations.

Blood cancer journal · Apr 8, 2026

Mitochondrial ACSS1 Links Acetate Metabolism to Pyrimidine Biosynthesis in Nutrient-Stressed B-Cell Lymphomas.

Cancer letters · Apr 7, 2026

Benefit of rituximab maintenance after first-line bendamustine-rituximab in patients with mantle cell lymphoma.

Blood advances · Feb 24, 2026

Integrative profiling strategies to guide personalized therapy in mantle cell lymphoma: a pilot study.

NPJ precision oncology · Nov 21, 2025

TCA cycle mode switch determines the fate of pirtobrutinib-tolerant persister cells in mantle cell lymphoma.

Blood · Nov 20, 2025

Treatment and outcomes of progression of disease post-CAR T-cell therapy in mantle cell lymphoma: a multicenter analysis.

Blood advances · Nov 11, 2025

Optical genome mapping reveals diverse mechanisms of cyclin activation in mantle cell lymphomas lacking IGH::CCND1.

Human pathology · May 1, 2025

Phase 2 trial of ibrutinib in previously untreated high-risk smoldering mantle cell lymphoma.

Leukemia & lymphoma · May 1, 2025

Targeting the DNA damage response through TBL1X in mantle cell lymphoma.

Blood advances · Apr 22, 2025

High-risk MCL: recognition and treatment.

Blood · Feb 13, 2025

Chimeric Antigen Receptor T-Cell-Associated Cholangiopathy: First Reported Case of a Complication of Chimeric Antigen Receptor T-Cell Therapy.

ACG case reports journal · Jan 1, 2025

Characteristics, treatment, and outcomes of mantle cell lymphoma with cutaneous involvement: a decade-long study at MD Anderson cancer center.

Leukemia & lymphoma · Nov 1, 2024

Author Correction: Longitudinal single-cell profiling reveals molecular heterogeneity and tumor-immune evolution in refractory mantle cell lymphoma.

Nature communications · Oct 7, 2024

Targeting CERS6-AS1/FGFR1 axis as synthetic vulnerability to constrain stromal cells supported proliferation in Mantle cell lymphoma.

Leukemia · Oct 1, 2024

Correction: Targeting CERS6-AS1/FGFR1 axis as synthetic vulnerability to constrain stromal cells supported proliferation in Mantle cell lymphoma.

Leukemia · Sep 1, 2024

Biclonal mantle cell lymphoma.

Blood · May 23, 2024

Efficacy and safety of brexucabtagene autoleucel CAR T-cell therapy with BTK inhibitors in the treatment of relapsed mantle cell lymphoma with central nervous system involvement.

Leukemia & lymphoma · May 1, 2024

Applying the EHA/EBMT grading for ICAHT after CAR-T: comparative incidence and association with infections and mortality.

Blood advances · Apr 23, 2024

TP53 mutation is frequent in mantle cell lymphoma with EZH2 expression and have dismal outcome when both are present.

Human pathology · Apr 1, 2024

SOX11+ Large B-Cell Neoplasms: Cyclin D1-Negative Blastoid/Pleomorphic Mantle Cell Lymphoma or Large B-Cell Lymphoma?

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · Feb 1, 2024

Optical genomic mapping is a helpful tool for detecting CCND1 rearrangements in CD5-negative small B-cell lymphoma: Two cases of leukemic non-nodal mantle cell lymphoma.

Human pathology · Feb 1, 2024

Final results and overall survival data from a phase II study of acalabrutinib monotherapy in patients with relapsed/refractory mantle cell lymphoma, including those with poor prognostic factors.

Haematologica · Jan 1, 2024