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Mitchell Smith

Professor of Medicine, Director of Cancer and Blood Disorders Division

GW Cancer Center, George Washington University · Washington, United States

About

Former Director of Lymphoid Malignancy Program at Cleveland Clinic and Fox Chase Cancer Center. Extensive clinical trial experience in lymphoma.

Specialties
Targeted therapiesImmunotherapyCAR-T therapy
Publications (16)

Live-cell Pick-Seq (LiP-Seq): Interrogating ultra-rare mantle cell lymphoma persistent cells after CART19 therapy.

Blood advances · Mar 19, 2026

Emerging immunotherapy advances for non-Hodgkin lymphomas: engaging T cells in the fight.

Hematology. American Society of Hematology. Education Program · Dec 5, 2025

Functional genomics and tumor microenvironment analysis reveal prognostic biological subtypes in Mantle cell lymphoma.

Nature communications · Nov 5, 2025

Copanlisib in combination with venetoclax in patients with relapsed/refractory mantle cell lymphoma.

Leukemia & lymphoma · Oct 31, 2025

NCCN Guidelines® Insights: B-Cell Lymphomas 3.2025.

Journal of the National Comprehensive Cancer Network : JNCCN · Oct 1, 2025

Translocations can drive expression changes of multiple genes in regulons covering entire chromosome arms.

Nucleic acids research · Aug 11, 2025

Safety and efficacy of acalabrutinib plus bendamustine and rituximab in patients with treatment-naïve or relapsed/refractory mantle cell lymphoma: phase Ib trial.

Haematologica · Mar 1, 2025

Evaluation of Bruton's Tyrosine Kinase (BTK) inhibition with alternative doses of ibrutinib in subjects with Chronic Lymphocytic Leukemia (CLL).

Cancer chemotherapy and pharmacology · Feb 28, 2025

Acalabrutinib plus venetoclax and rituximab in treatment-naive mantle cell lymphoma: 2-year safety and efficacy analysis.

Blood advances · Sep 10, 2024

Randomized study of induction with bendamustine-rituximab ± bortezomib and maintenance with rituximab ± lenalidomide for MCL.

Blood · Sep 5, 2024

Antibrush Border Antibody Disease: A Case Series.

Kidney medicine · Jul 1, 2024

CAR19 monitoring by peripheral blood immunophenotyping reveals histology-specific expansion and toxicity.

Blood advances · Jun 25, 2024

Editor's Note: Superior Efficacy of a Combined Epigenetic Therapy against Human Mantle Cell Lymphoma Cells.

Clinical cancer research : an official journal of the American Association for Cancer Research · May 1, 2024

Clinical features of neurotoxicity after CD19 CAR T-cell therapy in mantle cell lymphoma.

Blood advances · Mar 26, 2024

Ibrutinib as first-line therapy for mantle cell lymphoma: a multicenter, real-world UK study.

Blood advances · Mar 12, 2024

Final results and overall survival data from a phase II study of acalabrutinib monotherapy in patients with relapsed/refractory mantle cell lymphoma, including those with poor prognostic factors.

Haematologica · Jan 1, 2024