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Martin Dreyling

Professor of Medicine

Department of Medicine III, LMU University Hospital · Munich, Germany

About

Chair of the European MCL Network. Has led pivotal European trials defining the standard of care for MCL across age groups. Co-author of ESMO guidelines for MCL management.

Specialties
Clinical trialsEuropean MCL NetworkFrontline therapyGuidelines
Key Trials
European MCL Network trialsMCL ElderlyTRIANGLE
Publications (27)

Modern Management of Mantle Cell Lymphoma.

American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting · Jun 1, 2026

Addition of autologous stem-cell transplantation to an ibrutinib-containing first-line treatment in patients aged 18-65 years with mantle cell lymphoma (TRIANGLE): 4·5-year follow-up of a three-arm, randomised, open-label, phase 3 superiority trial of the European MCL Network.

Lancet (London, England) · May 16, 2026

Dissecting minimal residual disease dynamics to improve outcome prediction in mantle cell lymphoma: Data from the Fondazione Italiana Linfomi (FIL)-MCL0208 clinical trial.

HemaSphere · May 1, 2026

Brexucabtagene autoleucel for BTKi-naive relapsed/refractory mantle cell lymphoma: primary analysis of ZUMA-2 cohort 3.

Blood · Mar 19, 2026

Noninvasive genotyping and early disease dynamics demonstrate the efficacy of ibrutinib in combination with immunochemotherapy in patients with mantle cell lymphoma treated in the TRIANGLE trial.

Leukemia · Jan 1, 2026

A matching-adjusted indirect comparison of survival outcomes with pirtobrutinib (BRUIN) versus standard of care (SCHOLAR-2) in relapsed/refractory mantle cell lymphoma previously treated with a covalent Bruton tyrosine kinase inhibitor.

British journal of haematology · Jan 1, 2026

Marked survival gains in patients ≤ 65 years with advanced-stage mantle cell lymphoma: a pooled analysis of six randomized phase III trials, 1996-2020.

Haematologica · Oct 30, 2025

EHA-EU MCL network guidelines for diagnosis and treatment of mantle cell lymphoma.

HemaSphere · Oct 1, 2025

The MCL elderly III trial protocol: an international, randomized, open-label phase II trial to investigate the combinations of venetoclax, ibrutinib and rituximab or bendamustine, ibrutinib and rituximab in patients with treatment naive mantle cell lymphoma not eligible for dose-intensive treatment.

BMC cancer · Aug 25, 2025

Acalabrutinib Plus Bendamustine-Rituximab in Untreated Mantle Cell Lymphoma.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology · Jul 10, 2025

Prognostic biomarkers in MCL: insights from the SHINE trial on the impact of MCL35 score and TP53 mutation status.

Blood · Jun 19, 2025

First Line Therapy in Mantle Cell Lymphoma-The Role of BTKi in the Initial Treatment of Transplant-Eligible and -Ineligible Patients.

Hematological oncology · Jun 1, 2025

BR or R-CHOP induction with rituximab maintenance in untreated, transplant-ineligible patients with mantle cell lymphoma.

Blood advances · May 13, 2025

Validation of POD24 as a robust early clinical indicator of poor survival in mantle cell lymphoma from 1280 patients on clinical trials, a LYSA study.

Blood cancer journal · Apr 24, 2025

Treatment of relapsed/refractory MCL.

Blood · Feb 13, 2025

Conditional survival of younger patients with mantle cell lymphoma: Results from a randomized phase III trial of the European MCL Network.

British journal of haematology · Jan 1, 2025

To consolidate or not to consolidate: the role of autologous stem cell transplantation in MCL.

Hematology. American Society of Hematology. Education Program · Dec 6, 2024

Comprehensive genetic analysis by targeted sequencing identifies risk factors and predicts patient outcome in Mantle Cell Lymphoma: results from the EU-MCL network trials.

Leukemia · Dec 1, 2024

Unmet needs in relapsed/refractory mantle cell lymphoma (r/r MCL) post-covalent Bruton tyrosine kinase inhibitor (BTKi): a systematic literature review and meta-analysis.

Leukemia & lymphoma · Nov 1, 2024

Seven-year outcomes of venetoclax-ibrutinib therapy in mantle cell lymphoma: durable responses and treatment-free remissions.

Blood · Aug 22, 2024

Knowledge, skills, and confidence gaps impacting treatment decision making in relapsed/refractory chronic lymphocytic leukemia and mantle cell lymphoma: a quantitative survey study in France, Germany, and the United States.

BMC cancer · Aug 13, 2024

Biological and clinical determinants shaping heterogeneity in mantle cell lymphoma.

Blood advances · Jul 23, 2024

Rituximab, gemcitabine and oxaliplatin in relapsed or refractory indolent and mantle cell lymphoma: results of a multicenter phase I/II-study of the German Low Grade Lymphoma Study Group.

Annals of hematology · Jul 1, 2024

The addition of bortezomib to rituximab, high-dose cytarabine and dexamethasone in relapsed or refractory mantle cell lymphoma-a randomized, open-label phase III trial of the European mantle cell lymphoma network.

Leukemia · Jun 1, 2024

Ibrutinib combined with immunochemotherapy with or without autologous stem-cell transplantation versus immunochemotherapy and autologous stem-cell transplantation in previously untreated patients with mantle cell lymphoma (TRIANGLE): a three-arm, randomised, open-label, phase 3 superiority trial of the European Mantle Cell Lymphoma Network.

Lancet (London, England) · May 25, 2024

Predictive Value of Minimal Residual Disease for Efficacy of Rituximab Maintenance in Mantle Cell Lymphoma: Results From the European Mantle Cell Lymphoma Elderly Trial.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology · Feb 10, 2024

Indirect treatment comparison of brexucabtagene autoleucel (ZUMA-2) versus standard of care (SCHOLAR-2) in relapsed/refractory mantle cell lymphoma.

Leukemia & lymphoma · Jan 1, 2024