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Martin Dreyling

Professor of Medicine

Department of Medicine III, LMU University Hospital · Munich, Germany

About

Chair of the European MCL Network. Has led pivotal European trials defining the standard of care for MCL across age groups. Co-author of ESMO guidelines for MCL management.

Specialties
Clinical trialsEuropean MCL NetworkFrontline therapyGuidelines
Key Trials
European MCL Network trialsMCL ElderlyTRIANGLE
Publications (24)

Brexucabtagene autoleucel for BTKi-naive relapsed/refractory mantle cell lymphoma: primary analysis of ZUMA-2 cohort 3.

Blood · Mar 19, 2026

A matching-adjusted indirect comparison of survival outcomes with pirtobrutinib (BRUIN) versus standard of care (SCHOLAR-2) in relapsed/refractory mantle cell lymphoma previously treated with a covalent Bruton tyrosine kinase inhibitor.

British journal of haematology · Jan 1, 2026

Noninvasive genotyping and early disease dynamics demonstrate the efficacy of ibrutinib in combination with immunochemotherapy in patients with mantle cell lymphoma treated in the TRIANGLE trial.

Leukemia · Jan 1, 2026

Marked survival gains in patients ≤ 65 years with advanced-stage mantle cell lymphoma: a pooled analysis of six randomized phase III trials, 1996-2020.

Haematologica · Oct 30, 2025

EHA-EU MCL network guidelines for diagnosis and treatment of mantle cell lymphoma.

HemaSphere · Oct 1, 2025

The MCL elderly III trial protocol: an international, randomized, open-label phase II trial to investigate the combinations of venetoclax, ibrutinib and rituximab or bendamustine, ibrutinib and rituximab in patients with treatment naive mantle cell lymphoma not eligible for dose-intensive treatment.

BMC cancer · Aug 25, 2025

Acalabrutinib Plus Bendamustine-Rituximab in Untreated Mantle Cell Lymphoma.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology · Jul 10, 2025

Prognostic biomarkers in MCL: insights from the SHINE trial on the impact of MCL35 score and TP53 mutation status.

Blood · Jun 19, 2025

First Line Therapy in Mantle Cell Lymphoma-The Role of BTKi in the Initial Treatment of Transplant-Eligible and -Ineligible Patients.

Hematological oncology · Jun 1, 2025

BR or R-CHOP induction with rituximab maintenance in untreated, transplant-ineligible patients with mantle cell lymphoma.

Blood advances · May 13, 2025

Validation of POD24 as a robust early clinical indicator of poor survival in mantle cell lymphoma from 1280 patients on clinical trials, a LYSA study.

Blood cancer journal · Apr 24, 2025

Treatment of relapsed/refractory MCL.

Blood · Feb 13, 2025

Conditional survival of younger patients with mantle cell lymphoma: Results from a randomized phase III trial of the European MCL Network.

British journal of haematology · Jan 1, 2025

To consolidate or not to consolidate: the role of autologous stem cell transplantation in MCL.

Hematology. American Society of Hematology. Education Program · Dec 6, 2024

Comprehensive genetic analysis by targeted sequencing identifies risk factors and predicts patient outcome in Mantle Cell Lymphoma: results from the EU-MCL network trials.

Leukemia · Dec 1, 2024

Unmet needs in relapsed/refractory mantle cell lymphoma (r/r MCL) post-covalent Bruton tyrosine kinase inhibitor (BTKi): a systematic literature review and meta-analysis.

Leukemia & lymphoma · Nov 1, 2024

Seven-year outcomes of venetoclax-ibrutinib therapy in mantle cell lymphoma: durable responses and treatment-free remissions.

Blood · Aug 22, 2024

Knowledge, skills, and confidence gaps impacting treatment decision making in relapsed/refractory chronic lymphocytic leukemia and mantle cell lymphoma: a quantitative survey study in France, Germany, and the United States.

BMC cancer · Aug 13, 2024

Biological and clinical determinants shaping heterogeneity in mantle cell lymphoma.

Blood advances · Jul 23, 2024

Rituximab, gemcitabine and oxaliplatin in relapsed or refractory indolent and mantle cell lymphoma: results of a multicenter phase I/II-study of the German Low Grade Lymphoma Study Group.

Annals of hematology · Jul 1, 2024

The addition of bortezomib to rituximab, high-dose cytarabine and dexamethasone in relapsed or refractory mantle cell lymphoma-a randomized, open-label phase III trial of the European mantle cell lymphoma network.

Leukemia · Jun 1, 2024

Ibrutinib combined with immunochemotherapy with or without autologous stem-cell transplantation versus immunochemotherapy and autologous stem-cell transplantation in previously untreated patients with mantle cell lymphoma (TRIANGLE): a three-arm, randomised, open-label, phase 3 superiority trial of the European Mantle Cell Lymphoma Network.

Lancet (London, England) · May 25, 2024

Predictive Value of Minimal Residual Disease for Efficacy of Rituximab Maintenance in Mantle Cell Lymphoma: Results From the European Mantle Cell Lymphoma Elderly Trial.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology · Feb 10, 2024

Indirect treatment comparison of brexucabtagene autoleucel (ZUMA-2) versus standard of care (SCHOLAR-2) in relapsed/refractory mantle cell lymphoma.

Leukemia & lymphoma · Jan 1, 2024